Tropical sprue is an acquired chronic diarrheal disorder of unclear etiology affecting residents of and visitors to tropical regions. Patients usually present with . English Spanish online dictionary Term Bank, translate words and terms with different pronunciation options. ESPRUE TROPICAL trastorno de diarrea crónica con mala absorción y deficiencia nutricional etiología desconocida regiones tropicales.

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This article briefly reviews the management of tropical sprue and presents an algorithm for its investigation and management. J Gastroenterol Hepatol ; Tropical sprue is largely limited to within about 30 degrees north and south of the equator.

Terminal ileal resections can lead to vitamin B 12 deficiencies and bile salt malabsorption, whereas ileocaecal valve resections result in bacterial overgrowth causing malabsorption. Fever, uncommon in Caribbean patients, has been noted in almost a quarter of patients from southern India.

There was a mild intraepithelial lymphocytosis and eosinophil infiltrate in the colonic mucosa of half of the cases. Selective immunoglobulin Ig A deficiency is epsrue common and tropucal be associated with a flat mucosa and giardiasis.

esprue no tropical

Histologic findings suggesting tropical sprue in the appropriate clinical context include incomplete duodenal villous blunting without development of flat mucosa, frequent involvement of the terminal ileum with more marked inflammation and villous blunting than in the duodenum, and a conspicuous eosinophil infiltrate in the lamina propria. Malabsorption is an important clinical problem in tropical countries, typically presenting with chronic diarrhoea, glossitis, weight loss and multiple nutritional deficiencies.


Best Pract Res Clin Gastroenterol 19 — N Ewprue J Med 87— Upper Hematemesis Melena Lower Hematochezia. Sporadic tropical sprue is still an important cause of malabsorption in adults and in children in South Asia. It usually does not recur in people who get it during travel to affected regions.

It had been known for some time, following the discovery of new lands in the 15th and 16th centuries and their subsequent colonization, that some of the Europeans who came to live on these tropical islands of the Americas were afflicted with a new disease. J Pediatr Gastroenterol Nutr 41 — Scott Med J 38 — Basic sanitation is necessary to reduce fecal-oral contamination and the impact of environmental enteropathy in the developing world.

Sprue, both tropical and nontropical, has been a subject of great interest to the medical community ever since it was initially described over years ago. Gut 18 — Infection with this protozoan is common in the tropics and is often a cause of diarrhoeal illness in visitors to the tropics.

The disease was first described by William Hillary [11] in in Barbados.

Tropical sprue: revisiting an underrecognized disease.

Bacterial infections Intestinal tuberculosis is common in tropical countries. It may manifest with many fropical syndromes, including obstruction and malabsorption syndromes. Clubbing of the fingers is characteristic and abdominal masses may be palpated on physical examination. A milder form of chronic diarrhoea, steatorrhoea and a marked weight loss follows this.

Pancreatic disease Tropical pancreatitis Idiopathic chronic calcific pancreatitis is endemic in several tropical regions esprud the Indian subcontinent and southern Africa. Scand J Gastroenterol 40 — Quantitative stool fat estimation is the most reliable test of malabsorption in the tropics.


Tropical Medicine Central Resource

Clinical manifestations A typical patient with tropical sprue is an adult who presents with chronic diarrhoea, glossitis, bloating, prominent bowel sounds and weight loss. Am J Trop Med Hyg 10 — Persistent diarrhea in the returned traveler. Malabsorption following the acute illness.

topical Diagnosis of tropical sprue, parasitic disorders, IPSID and other specific conditions can be made on the basis of biopsy results. J Pathol 98 [ PubMed ].

Tropical malabsorption

Primary immunodeficiency presenting with gastrointestinal disease in the tropics. D Espruue – This is identified by quick response to treatment with tetracycline or other antibiotics.

Hypoproteinaemia secondary to loss of mucosal surface, protein loss and pancreatic insufficiency. Gut 29 — Nutrient malabsorption in tropical sprue arises from involvement of both the proximal and distal espprue intestine. Coeliac disease in developing countries: Bacterial colonisation of jejunal mucosa in acute tropical sprue. Assessment of early and delayed responses in vitamin B12 absorption during antibiotic therapy in tropical malabsorption.

The villi are shorter, crypts are more elongated and there are increased numbers of lymphocytes in the lamina propria.